Thaler has also appealed to the Supreme Court over rejected U.S. Patent and Trademark Office applications, urging the court to decide whether or not AI-generated inventions are eligible for U.S. patent protection. The Trump administration had been placing pressure on the court to deny hearing Thaler's copyright case, CNBC reports.
PacBio was founded in 2004 to develop sequencing methods based on work done in the labs of biophysicist Watt Webb and engineer Harold Craighead, both at Cornell University. The previous year, the two had collaborated to create zero-mode waveguides (ZMWs): small containers just big enough to hold a single DNA polymerase and containing tiny holes at the bottom through which light could be detected. They were able to fix a DNA polymerase to the bottom of a ZMW and detect the incorporation of individual fluorescent “C” nucleotides through the holes, which fed into a microscope capable of detecting light emissions.
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